{"id":81,"date":"2010-12-09T14:13:27","date_gmt":"2010-12-09T21:13:27","guid":{"rendered":"http:\/\/theloungeisback.wordpress.com\/?p=81"},"modified":"2010-12-09T14:13:27","modified_gmt":"2010-12-09T21:13:27","slug":"surgeon-general-new-report-on-smoking-cigarettes-are-bad-mkay","status":"publish","type":"post","link":"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=81","title":{"rendered":"Surgeon General new report on smoking &#8230; cigarettes are bad, M&#8217;kay"},"content":{"rendered":"<p><a href=\"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2010\/12\/smoking-effects.jpg?ssl=1\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" data-attachment-id=\"82\" data-permalink=\"https:\/\/pepesnonsmokingpartytimelounge.com\/?attachment_id=82\" data-orig-file=\"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2010\/12\/smoking-effects.jpg?fit=795%2C521&amp;ssl=1\" data-orig-size=\"795,521\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;Pierre&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;1291902212&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;}\" data-image-title=\"smoking effects\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2010\/12\/smoking-effects.jpg?fit=474%2C311&amp;ssl=1\" src=\"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2010\/12\/smoking-effects.jpg?resize=474%2C310&#038;ssl=1\" alt=\"\" title=\"smoking effects\" width=\"474\" height=\"310\" class=\"alignleft size-full wp-image-82\" srcset=\"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2010\/12\/smoking-effects.jpg?w=795&amp;ssl=1 795w, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2010\/12\/smoking-effects.jpg?resize=300%2C196&amp;ssl=1 300w\" sizes=\"auto, (max-width: 474px) 100vw, 474px\" \/><\/a><br \/>\nOK, what has gotten a lot of press from a truly extensive Surgeon General&#8217;s report on cigarettes released yesterday is a conclusion that &#8220;there is no safe level of cigarette smoke.&#8221;<\/p>\n<p>The media has turned this into &#8220;just one cigarette can kill you.&#8221; Unfortunately, the report does contain a passage that just a few minutes of cigarette smoke can give a person with heart disease a heart attack. Well, having someone sneak up on you from behind and say, &#8220;Boo!&#8221; can give you a heart attack if you have serious heart disease. It&#8217;s a really stupid point.<\/p>\n<p>The real crux of the report, which the media has missed somewhat, is that it examines how cigarettes cause various forms of cancer and lung disease.<br \/>\nIn summary:<br \/>\n\u2022 The chemicals and toxicants in tobacco smoke damage DNA, which can lead to cancer. Nearly one-third of all cancer deaths every year are directly linked to smoking. Smoking causes about 85% of lung cancers in the U.S.<br \/>\n&#8226;Exposure to tobacco smoke quickly damages blood vessels throughout the body and makes blood more likely to clot. This damage can cause heart attacks, strokes, and even sudden death.<br \/>\n&#8226; The chemicals in tobacco smoke inflame the delicate lining of the lungs and can cause permanent damage that reduces the ability of the lungs to exchange air efficiently and leads to chronic obstructive pulmonary disease (COPD), which includes emphysema and chronic bronchitis.<\/p>\n<p>I found the lung cancer chapter the most interesting. Sure enough, here is the conclusion I was looking for:<\/p>\n<blockquote><p>&#8220;There is consistent evidence that a combination of polymorphisms in the CYP1A1 and GSTM1 genes leads to higher DNA adduct levels in smokers and higher relative risks for lung cancer than in those smokers without this genetic profile.<br \/>\n&#8220;Exposure to cigarette smoke carcinogens leads to DNA damage and subsequent mutations in TP53 and KRAS in lung cancer.&#8221;<\/p><\/blockquote>\n<p>So, here&#8217;s the thing to wrap your heads around. <em>Smoking fucks with your DNA<\/em>. It isn&#8217;t just irritating the cells of your lungs, it&#8217;s actually <em>changing the DNA<\/em> of those cells.<\/p>\n<p>The various cancers mentioned by the report were lung, mouth, throat, stomach, pancreas, bladder, kidney and leukemia. Surprisingly, lymphoma was not mentioned. I had always thought there was an increased risk of lymphoma if you smoked, but this report doesn&#8217;t mention that, so I suppose not.<\/p>\n<p>One of the things that has long baffled scientists is why most smokers don&#8217;t get lung cancer. Somewhere between 10 to 20 percent do, depending on what study you read. Why don&#8217;t the 80 or other 90 percent get lung cancer is smoking is carcinogenic?<\/p>\n<p>The answer apparently is in genetics, which the report refers to above, and I was hoping it would talk about that. People with a certain gene are more prone to lung cancer. If they smoke and have this gene, they are at extreme risk of lung cancer. If they don&#8217;t smoke, they are still at elevated risk of lung cancer. That&#8217;s why 10 percent of men who get lung cancer aren&#8217;t smokers, and 20 percent of women. Perhaps there are other environmental factors, such as radon or air pollution. But, the fact remains, that roughly 85 percent of the people who get lung cancer are smokers.<\/p>\n<p>So, if you don&#8217;t have this gene and smoke, you will probably never get lung cancer. You may die in your 50s of heart disease or die from COPD or some other form of cancer, but you probably won&#8217;t get lung cancer. So, you&#8217;re not somehow magically out of the woods if you don&#8217;t have this gene. It isn&#8217;t that simple.<br \/>\nAnyway, here is the <a href=\"http:\/\/\">press release<\/a> on this report. You can download the whole <a href=\"http:\/\/www.surgeongeneral.gov\/library\/tobaccosmoke\/index.html\">700-page document<\/a> if you wish. Or you can just download the executive summary.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>OK, what has gotten a lot of press from a truly extensive Surgeon General&#8217;s report on cigarettes released yesterday is a conclusion that &#8220;there is no safe level of cigarette smoke.&#8221; The media has turned this into &#8220;just one cigarette can kill you.&#8221; Unfortunately, the report does contain a passage that just a few minutes &hellip; <a href=\"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=81\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Surgeon General new report on smoking &#8230; cigarettes are bad, M&#8217;kay<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":82,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[35,64,69,1],"tags":[599,174,186],"class_list":["post-81","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lung-cancer","category-surgeon-general","category-tobacco-2","category-uncategorized","tag-lung-cancer","tag-smoking","tag-surgeon-general-2"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2010\/12\/smoking-effects.jpg?fit=795%2C521&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p4hpEa-1j","jetpack-related-posts":[{"id":1838,"url":"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=1838","url_meta":{"origin":81,"position":0},"title":"More 50-year anniversary stories: Cigarettes do more than cause lung cancer","author":"Pepe Lepew","date":"January 20, 2014","format":false,"excerpt":"Lots of news outlets are doing 50-year anniversary stories on the Surgeon General's landmark report. I'm posting links to a couple of them. This one is from RawStory (Reprinted from a French news service -- thanks to Haruko for the link and there she is posting away and a bunch\u2026","rel":"","context":"In &quot;smoking&quot;","block_context":{"text":"smoking","link":"https:\/\/pepesnonsmokingpartytimelounge.com\/?cat=57"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/A-woman-smokes-a-cigarette-in-the-pedestrian-plaza-located-in-Times-Square-AFP.jpg?fit=615%2C345&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/A-woman-smokes-a-cigarette-in-the-pedestrian-plaza-located-in-Times-Square-AFP.jpg?fit=615%2C345&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/A-woman-smokes-a-cigarette-in-the-pedestrian-plaza-located-in-Times-Square-AFP.jpg?fit=615%2C345&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":1346,"url":"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=1346","url_meta":{"origin":81,"position":1},"title":"50th Anniversary of Surgeon General&#8217;s Report on smoking","author":"Pepe Lepew","date":"January 7, 2014","format":false,"excerpt":"Next week is the 50th anniversary of the groundbreaking U.S. Surgeon General's report on cigarettes. This report was the result of more than a decade of studies and research into the growing suspicion of a connection between smoking and lung cancer. A lot of this is documented pretty well in\u2026","rel":"","context":"In &quot;smoking&quot;","block_context":{"text":"smoking","link":"https:\/\/pepesnonsmokingpartytimelounge.com\/?cat=57"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/mad-men-season-3-poster-11.jpg?fit=1200%2C940&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/mad-men-season-3-poster-11.jpg?fit=1200%2C940&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/mad-men-season-3-poster-11.jpg?fit=1200%2C940&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/mad-men-season-3-poster-11.jpg?fit=1200%2C940&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2014\/01\/mad-men-season-3-poster-11.jpg?fit=1200%2C940&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":3928,"url":"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=3928","url_meta":{"origin":81,"position":2},"title":"Mike Pence: Cigarettes aren&#8217;t deadly &#8230; yes, he really said this","author":"Pepe Lepew","date":"August 7, 2016","format":false,"excerpt":"In case you needed another reason not to vote for Donald Trump\/Mike Pence. Pence, the governor or Indiana, once wrote an oped piece about how cigarette smoking is not dangerous. I'm serious. He really did. I'm not talking secondhand smoke, either. Pence wrote his column about smoking ... period. And\u2026","rel":"","context":"In &quot;Mike Pence&quot;","block_context":{"text":"Mike Pence","link":"https:\/\/pepesnonsmokingpartytimelounge.com\/?cat=831"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2016\/08\/abc_tw_pence_150329a1-800x430.jpg?fit=800%2C430&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2016\/08\/abc_tw_pence_150329a1-800x430.jpg?fit=800%2C430&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2016\/08\/abc_tw_pence_150329a1-800x430.jpg?fit=800%2C430&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2016\/08\/abc_tw_pence_150329a1-800x430.jpg?fit=800%2C430&ssl=1&resize=700%2C400 2x"},"classes":[]},{"id":2926,"url":"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=2926","url_meta":{"origin":81,"position":3},"title":"Report: Smoking&#8217;s death toll higher than previously thought","author":"Pepe Lepew","date":"February 15, 2015","format":false,"excerpt":"Wow, this story is a big wow. I had many an argument back in the day with Smoker's Club weasels: that the death toll from smoking (440,000 a year in the U.S.) has been exaggerated by anti-smoking fanatics and the government. Well, according to a new study released this week\u2026","rel":"","context":"In &quot;New England Journal of Medicine&quot;","block_context":{"text":"New England Journal of Medicine","link":"https:\/\/pepesnonsmokingpartytimelounge.com\/?cat=439"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2015\/02\/sgr_figure2_500.jpg?fit=500%2C350&ssl=1&resize=350%2C200","width":350,"height":200},"classes":[]},{"id":876,"url":"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=876","url_meta":{"origin":81,"position":4},"title":"Pot smoking doesn&#8217;t cause lung disease: The lung cancer gene, part 1","author":"Pepe Lepew","date":"February 7, 2012","format":false,"excerpt":"A study that came out last month determined that occasional post smoking doesn't cause near the damage to lungs as cigarette smoking. The study followed 5,115 regular pot smokers over the course of 20 years. This reminds me very much of a study done about 5 years ago showing that\u2026","rel":"","context":"In &quot;Lung cancer&quot;","block_context":{"text":"Lung cancer","link":"https:\/\/pepesnonsmokingpartytimelounge.com\/?cat=35"},"img":{"alt_text":"marijuana","src":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2012\/02\/marijuana.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":3181,"url":"https:\/\/pepesnonsmokingpartytimelounge.com\/?p=3181","url_meta":{"origin":81,"position":5},"title":"FDA study: Cigars are not safer than cigarettes","author":"Pepe Lepew","date":"April 24, 2015","format":false,"excerpt":"\u00a0 This story actually surprised me a little bit, because prior studies had suggested that cigarettes were actually more dangerous than cigars because cigarette tobacco is a different kind of tobacco from cigar tobacco, and it is also cured differently. Allan Brandt also talked about this somewhat in his excellent\u2026","rel":"","context":"In &quot;centers for disease control&quot;","block_context":{"text":"centers for disease control","link":"https:\/\/pepesnonsmokingpartytimelounge.com\/?cat=13"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2015\/04\/aptopix-cuba-cigar-festival-jpeg-0a3c0_23912670-e1429907320428.jpg?fit=1000%2C646&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2015\/04\/aptopix-cuba-cigar-festival-jpeg-0a3c0_23912670-e1429907320428.jpg?fit=1000%2C646&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2015\/04\/aptopix-cuba-cigar-festival-jpeg-0a3c0_23912670-e1429907320428.jpg?fit=1000%2C646&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/pepesnonsmokingpartytimelounge.com\/wp-content\/uploads\/2015\/04\/aptopix-cuba-cigar-festival-jpeg-0a3c0_23912670-e1429907320428.jpg?fit=1000%2C646&ssl=1&resize=700%2C400 2x"},"classes":[]}],"_links":{"self":[{"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=\/wp\/v2\/posts\/81","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=81"}],"version-history":[{"count":0,"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=\/wp\/v2\/posts\/81\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=\/wp\/v2\/media\/82"}],"wp:attachment":[{"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=81"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=81"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pepesnonsmokingpartytimelounge.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=81"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}